testosterone and dihydrotestosterone) receptors and inhibit the protein synthesis induced by the anabolic effects of androgens. DIM – Diindolylmethane is an androgen antagonist! While there are promising benefits that can come with taking DIM, there are some potential side effects to take note. In light of this, are there any DIM adverse consequences? It may do so in several ways. Research seems to show associations between hyponatremia and osteoporosis. But are the possible benefits worth the risk? Hello Marva, DIM 200, and DIM 250 Complex are different supplements. DIM side effects. Side effects of DIM supplements are common and may include headaches, dehydration, as well as joint pain, aching, or cracking. Diindolylmethane (DIM) is a metabolite of Indole-3-carbinol (I3C), a compound found in cruciferous vegetables including broccoli, cabbage and cauliflower.It is the most studied of all I3C metabolites and is thought to be superior to IC3 as a chemoprotective compound for breast cancer and prostate cancer .. DIM demonstrated anti-inflammatory , antiproliferative and chemopreventive effects … The list of side effects below is not a definite one and you should consult your doctor about other potential side effects based on your health condition and possible drug or supplement interactions. DIM blocks the effects of testosterone. Higher doses (greater than 100mg) of isolated pure DIM can saturate tissues and block androgen (e.g. When taken correctly in the small amounts found in foods, diindolymethane is likely safe. It further confirmed results and safety reported from previous studies in adult humans and the adult animal model. DIM possesses hormone-modulating effects. Diindolylmethane may cause a decrease in the amount of sodium in the body . DIM supplements is commonly taken in doses of 100 mg to 200 mg. Side Effects. Diindolylmethane is formed in the body from plant substances contained in “cruciferous” vegetables such as cabbage, Brussels sprouts, cauliflower, and broccoli. After all, any supplement, even if it’s all natural, may have negative side effects. Studies suggest it protects the body from xenoestrogens, compounds that mimic and intensify the effects of estrogen. DIM Supplement Side Effects and Dosage. The data from this study indicated that DIM is safe, with no significant side effects found, even with DIM at a dose 10 times higher than that currently used in practice. Diindolylmethane Side Effects Rash, nausea, vomiting, headache, arthralgia and hot flashes have been reported. DIM side effects caused by hyponatremia are far more likely to be experienced by the elderly. Learn more about Diindolylmethane uses, benefits, side effects, interactions, safety concerns, and effectiveness. Notably, falling down is the most prevalent cause of accidental death among people 65 and older. Keep in mind that the safety profile of DIM is relatively unknown, given the lack of well-designed clinical studies. They have different amounts of DIM per capsule (200 or 250mg), and the DIM 250 Complex also contains an array of different supportive ingredients designed to maximize usefulness for use during menopause, including various vegetable powders, Broccoli seed extract, Vitamin D-3, and herbal Dong Quai. Side effects mentioned in DIM Elite reviews on Amazon include an irregular menstrual cycle, insomnia, increased acne, and hair loss. Some common side effects that occur following the usage of DIM include a rash with eosinophilia as well as central serous chorioretinopathy . Nature's Way DIM Plus is used for estrogen metabolism which is the breakdown of estrogen in the liver attempting to eradicate it. DIM has also been shown to favorably alter the ratios of “good” to “bad” estrogen. WebMd.com claims DIM is most likely safe. Diindolylmethane (DIM) reduces the level of "bad estrogen" (16-hydroxyestrone estrogen metabolites) while increasing "good" estrogen (2-hydroxyestrone estrogen metabolites). DIM is safe for most individuals, but you may experience some mild detox-like symptoms including: Fatigue; Headache; Nausea; Dark-colored urine; Changes in menstrual cycle Diindolylmethane Side Effects. Also been shown to favorably alter the ratios of “ good ” to “ bad ” estrogen of. Correctly in the amount of sodium in the body and intensify the effects of DIM supplements common! Confirmed results and safety reported from previous studies in adult humans and the adult animal model nature Way! 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